Description
Indometacin is a non-steroidal anti-inflammatory drug (NSAID) used to reduce pain, swelling, and stiffness caused by inflammation. It is commonly prescribed for arthritis, including rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and acute gout attacks.
Uses
- Relief of joint pain, swelling, and stiffness in arthritis
- Treatment of acute gout flares
- Management of other inflammatory conditions as prescribed by a doctor
How it works
Indometacin works by reducing the production of prostaglandins—chemicals in the body that cause inflammation, pain, and fever.
Safety Information
- Use the lowest effective dose for the shortest duration needed
- Take with food or milk to reduce stomach irritation
- Not intended for long-term use unless advised by a healthcare professional
Possible Side Effects
Common side effects may include:
- Stomach pain, indigestion, nausea, or heartburn
- Headache or dizziness
- Drowsiness
Less common but serious side effects:
- Stomach ulcers or bleeding
- High blood pressure
- Kidney or liver problems
- Increased risk of heart attack or stroke with prolonged use
Seek medical attention if you experience black stools, severe stomach pain, chest pain, shortness of breath, or swelling of the face or limbs.
Caution
Use with caution if you:
- Have a history of stomach ulcers or bleeding
- Have heart, kidney, or liver disease
- Are elderly
- Are taking blood thinners, steroids, or other NSAIDs
Avoid alcohol while taking indometacin, as it increases the risk of stomach bleeding.
Contraindications
Indometacin should not be used if you:
- Are allergic to indometacin, aspirin, or other NSAIDs
- Have active stomach or intestinal bleeding
- Have severe heart failure
Are in the third trimester of pregnancy


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