Description
What is Zomig Nasal Spray?
Zomig (zolmitriptan) nasal spray is a fast-acting treatment used to relieve acute migraine attacks. It belongs to a group of medicines called triptans, which are specifically designed to treat migraine symptoms rather than general headaches.
Zomig is intended to be used as soon as a migraine begins, helping to reduce pain and associated symptoms such as nausea, sensitivity to light, and sensitivity to sound.
How Zolmitriptan Nasal Spray Works
Zolmitriptan works by targeting the underlying causes of migraine. It:
- Narrows widened blood vessels in the brain
- Blocks pain signals in the nervous system
- Reduces inflammation linked to migraine attacks
The nasal spray format allows the medication to be absorbed quickly through the nasal lining, making it particularly useful for people who experience nausea or vomiting during migraines.
Benefits of Zomig Nasal Spray
- Rapid relief – works quickly due to nasal absorption
- Ideal for nausea – no need to swallow tablets
- Migraine-specific treatment – targets the root cause of migraine symptoms
- Convenient and easy to use
- Effective when standard painkillers are insufficient
How to Use Zomig Nasal Spray
- Use at the first sign of a migraine attack
- Administer one spray into one nostril
- If symptoms return, a second dose may be used after at least 2 hours, if advised
- Do not exceed the prescribed maximum daily dose
Always follow the instructions provided on the patient information leaflet.
Possible Side Effects
Common side effects
- Unusual or bitter taste
- Nasal discomfort or irritation
- Dizziness or drowsiness
- Feeling tired
Serious side effects (rare)
- Chest pain or tightness
- Irregular heartbeat
- Severe abdominal pain
- Signs of stroke (such as weakness or difficulty speaking)
- Allergic reactions, including swelling or difficulty breathing
Seek urgent medical attention if you experience serious side effects.
Risks and Safety Considerations
While effective, zolmitriptan may not be suitable for everyone. Potential risks include:
- Increased risk of heart-related side effects in some individuals
- Serotonin syndrome when combined with certain antidepressants
- Medication overuse headache if used too frequently
Cautions
Speak to our clinicians before using Zomig if you:
- Have high blood pressure, diabetes, or high cholesterol
- Smoke or have risk factors for heart disease
- Are taking antidepressants or other migraine medications
- Are pregnant or breastfeeding
Zomig should only be used for confirmed migraine diagnoses, not other types of headaches.
Contraindications
Do not use Zomig nasal spray if you:
- Have a history of heart disease or stroke
- Have uncontrolled high blood pressure
- Have taken another triptan or ergot-type medication within 24 hours
- Are currently taking or have recently taken MAO inhibitor medicines
Further information about the medication:
Patient information leaflet:


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